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Alternatives to OpenManus
A general-purpose AI agent written in Python, built as an open alternative to Manus. The listings below can replace it for an important use case. Each note says what changes if you switch.
The original
OpenManus
A general-purpose AI agent written in Python, built as an open alternative to Manus.
Replacements
Listings that take over the same core job as OpenManus.
Manus
An autonomous AI agent that carries out multi-step tasks such as building slides and websites.
Manus is the hosted commercial agent OpenManus imitates, running tasks on its servers across web, desktop, mobile and Slack, with no Python setup needed.
Suna
An open AI agent system from Kortix for research and browser tasks that you can self-host.
Suna is a self-hosted general-purpose agent from Kortix for research and browser tasks, though self-hosting involves several services.
AutoGPT
A platform for building, deploying and running autonomous AI agents, which you can host yourself.
AutoGPT is a large self-hosted platform for building and running autonomous agents with Docker, including both a newer platform and the classic agent.
Agent Zero
A self-hosted personal AI agent framework that uses the computer as a tool and runs in Docker.
Agent Zero is a self-hosted personal agent in Docker that uses the computer as a tool, with a web interface and plugin extensions.
MindsHub (formerly MindsDB)
Open source agent workspace for research, coding and business tasks.
MindsHub is an MIT-licensed agent workspace for research, coding and business tasks with a web interface and self-hosting option.
gptme
An open-source AI agent for the terminal that writes code, runs shell commands and browses the web.
gptme is an open-source terminal agent that runs shell commands, edits files and browses the web, designed as a hackable base for your own agent.
MiniMax Agent
A general-purpose AI agent from MiniMax for research, coding, analysis and content tasks in the browser.
MiniMax Agent is a hosted general-purpose agent in the browser with nothing to install, but tasks and data are processed on MiniMax servers.
Also worth comparing
These listings name OpenManus as their own alternative, so the relationship runs both ways.
Goose
Run an extensible AI assistant on your desktop or in a terminal.
OpenManus is a Python general-purpose agent with MCP and multi-agent flows, run from the command line or Docker with configuration files.
Letta
A command-line AI agent from the Letta research lab whose memory and capabilities build up with use.
OpenManus is a Python general-purpose agent supporting MCP and multi-agent flows, run from the command line or in Docker.
Similar software
Related functionality, not a direct replacement.
GPT Researcher
An open-source autonomous agent that researches the web and local documents and writes cited reports.
Cua
Open-source infrastructure for running computer-use AI agents in sandboxed virtual machines across operating systems.
UI-TARS Desktop
An open-source desktop GUI agent from ByteDance that operates your computer using multimodal AI models.