Compare software

AvogadroChemCanvas
Free

Free and open source.

 Free

Free and open source under GPL-3.0-or-later.

Windows, macOS, Linux Windows, Linux
  • Handles systems of thousands of atoms
  • Force fields quickly clean up sketched structures
  • Reads and writes SMILES, Molfile, MRV and CDXML
  • Exports to PDF, PNG and editable SVG
  • Assumes some chemistry background
  • Not a full simulation package on its own
  • No macOS build
  • Supports fewer file formats than commercial chemistry suites
Downloadable app Downloadable app
Open source Open source
License not stated License: GPL-3.0-or-later
No account needed No account needed
Works offline Works offline

Checked September 23, 2026

Checked October 1, 2026

Catalog facts only. Anything “not stated” is unconfirmed. Check full listings for details.