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ChemCanvasAvogadro
Free

Free and open source under GPL-3.0-or-later.

 Free

Free and open source.

Windows, Linux Windows, macOS, Linux
  • Reads and writes SMILES, Molfile, MRV and CDXML
  • Exports to PDF, PNG and editable SVG
  • Handles systems of thousands of atoms
  • Force fields quickly clean up sketched structures
  • No macOS build
  • Supports fewer file formats than commercial chemistry suites
  • Assumes some chemistry background
  • Not a full simulation package on its own
Downloadable app Downloadable app
Open source Open source
License: GPL-3.0-or-later License not stated
No account needed No account needed
Works offline Works offline

Checked October 1, 2026

Checked September 23, 2026

Catalog facts only. Anything “not stated” is unconfirmed. Check full listings for details.